Correlation Between BMI, Hba1c And Fasting Lipid Profile in Patients Presenting with Acute Coronary Syndrome and Their Relationship with CVD Risk

Abstract

Context: Cardiovascular Disease has been historically correlated with Diabetes, Obesity and increased circulating lipids. HbA1c
is a reliable marker of Diabetes as well as being used to predict the occurrence of macro and micro vascular complications. BMI
is a measure of the body fat and the Fasting lipid profile is an essential part of any CVD prevention. Aims: This study aimed to
reveal the correlation of HbA1c with BMI, Fasting lipid profile and to compare them with the predicted CVD risk. Settings and
Design: The study subjects were part of a Cross sectional validation study to compare different Cardiovascular Disease risk score calculators in a Tertiary care hospital. Methods and Material: A total of 773 people presenting with Acute Coronary Syndrome were selected and their baseline characteristics, laboratory parameters analyzed. Statistical analysis used: The statistical analysis was done by calculating the p value with the Chi square test. Results: The Chi square test gave an insignificant p value of 0.9783 which shows that the higher HbA1c does not translate to a higher BMI. Conclusions: The BMI and the HbA1c correlated with the LDL in the Lipid profile. The BMI and HbA1c individually correlated well with a high risk of developing acute Coronary Syndrome. Thus, the take home message is, a normal BMI does not guarantee a decreased Cardiovascular risk in the Indian population due to the prevalence of metabolic obesity