PREVALENCE OF METABOLIC SYNDROME PHENOTYPES USING WHO, NCEP ATP III, MODIFIED NCEP ATP III, IDF AND HARMONIZED CRITERIA: A SYSTEMATIC REVIEW WITH SPECIAL REFERENCE TO ASIAN INDIANS

Abstract

Background: Metabolic syndrome is the accumulation of cardiovascular disease components in an individual which increases the risk of several non-communicable diseases. Several diagnostic criteria for determining MS have been proposed by different organizations but the disparities in outcomes using these criteria are well-evident in numerous literature. Objective: The present review aims to enlighten the hindrance in understanding the actual prevalence of MS globally using different cut-offs in a single study as well as the prevalence of MS phenotypes in AsianIndians using hitherto available definitions along with Asian Indian specific Cut-offs. Methodology: Literature search was done from the peer-reviewed journals using the following
keywords: ‘Metabolic syndrome’, ‘Asian Indian’, ‘global population’, ‘NCEP ATP III’, ‘modified NCEP ATP III’, ‘IDF criteria’, ‘Harmonized criteria’, ‘WHO criteria’ and ‘Asian specific criteria’. 57 papers have been systematically reviewed out of which 30 papers were retrieved from Google Scholar, 11 papers from PubMed, 10 papers from Researchgate, and 6 papers by Google searching. Conclusion: There is an urgent need for using a uniform criterion for determining MS in any of the global population and as it also hinders in determining the diagnostic criteria for pediatric MS. Asian Specific criterion is a more significant way for defining MS in the Asian Indian population.