‘’ Review On Prognosis And Management Of Organophosparus Poisioning’’

Authors

  • Dr. Gaurav R. Dehadray, Dr. Rajat P. Naik Author

DOI:

https://doi.org/10.48047/

Keywords:

Atropine, Calcium channel blocking drug, Diagnosis, Fresh frozen plasma, hemoperfusion, magnesium sulfate, Management, Organophosphate, Poisoning, Oxime, Prognosis, Serum albumin, Sodium bicarbonate

Abstract

The high annual mortality rate of organophosphorus (OP) poisoning indicates that the treatment is 
mostly ineffective in this regard. It has been suggested to add calcium channel blocking (CCB) drugs 
or magnesium sulphate (MgSO4) to normal care to decrease the release of acetylcholine (ACh) at the 
cholinergic synapse. Moreover, the diagnosis of OP poisoning is chiefly based on clinical evidence. 
Oximes and atropine are the recognized antidotes of OP. However, low-priced medications such as 
MgSO4 and sodium bicarbonate (NaHCO3), as well as novel adjunct therapies, have been introduced 
recently.

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Published

2019-02-10

Issue

Vol. 10 No. 1 (2019): volume 10 issue 1 (2019)

Section

Articles