"Nitric Oxide Dysfunction in Hypertension: A Systematic Review of Pathophysiological Mechanisms and Clinical Implications"

Abstract

This systematic review explores the intricate relationship between nitric oxide (NO) bioactivity and hypertension, drawing upon evidence from diverse geographical regions. The study synthesizes findings from research conducted in Switzerland, the USA, the United Kingdom, and India, among others, to elucidate the multifaceted mechanisms underlying hypertension pathogenesis. Key findings indicate that impaired NO bioactivity contributes significantly to hypertension, manifesting