Assessment of Oncological outcomes in Patients with Locally-Advanced Rectal Cancer Treated with Neoadjuvant Chemoradiation followed by Total Mesorectal Excision in a Tertiary Care Centre

Abstract

Background 
Locally-advanced rectal cancer (LARC) differ from early rectal cancer in terms of requiring multimodal preoperative management. This strategy has been shown to achieve higher rates of locoregional control of disease and thereby improving overall and disease-free survival. Through this study, we try to analyse the oncological outcomes in locally-advanced rectal cancer treated with neoadjuvant chemoradiation (CRT) followed by total mesorectal excision (TME).