A RANDOMIZED CLINICAL TRIAL COMPARING PLAIN BUPIVACAINE AND DEXMEDETOMIDINE AS ADJUVANT TO BUPIVACAINE IN PAEDIATRIC CAUDAL ANESTHESIA

Abstract

Background Many local anesthetic drugs of variable concentration are used. Bupivacaine is a long-acting amide local anaesthetic that has provided reliable anaesthesia and analgesia with differential motor-sensory blockade for more than 40 years. Caudal opioid have advantages of prolonging duration of analgesia, but has side effects such as nausea, vomiting, pruritis and late respiratory depressionHence here is an attempt to study, addition of dexmedetomidine with striking lack of respiratory depressant effect, when given as adjuvant with caudal bupivacaine