Correlation between Glycated Hemoglobin, Non-HDL Cholesterol, hs-CRP and Fructosamine in Diabetic and Healthy Individuals

Abstract

Background: Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disorder characterized by hyperglycemia, insulin resistance, and altered lipid metabolism, increasing the risk of cardiovascular diseases and other complications. Monitoring glycemic control through HbA1c is essential, but it may not fully capture the broader metabolic disturbances associated with T2DM, including lipid abnormalities and systemic inflammation. This study aims to explore the correlations between HbA1c and various metabolic parameters in T2DM patients, including fasting blood sugar (FBS), lipid profile (total cholesterol, LDL-C, HDL-C, non-HDL-C, triglycerides), high-sensitivity C-reactive protein (hs-CRP), and fructosamine.