Molecular characterization of Extended Spectrum Beta Lactamases among Uropathogenic isolates of Klebsiella pneumoniae by Real time Multiplex PCR in a tertiary care hospital in Indore, Central India.

Abstract

Introduction- ESBL producing Klebsiella pneumoniae are globally responsible for an increasing number of UTIs with severe morbidity and death. Worldwide, ESBLs have become an important concern for hospitalised patients and have been linked to numerous outbreaks. By using molecular techniques to identify prevalent ESBL genes like TEM, SHV, and CTX-M in ESBLproducing bacteria and their pattern of antibiotic resistance, it is possible to gain insight into the epidemiology of ESBLs and support targeted antimicrobial therapy.