Study Of Correlation of Lymphocytes and ADA Levels in Suspected Cases of Bilateral Tubercular Pleural Effusion
Keywords:
tubercular pleural effusion, non-tubercular pleural effusion, lymphocytes, adenosine deaminase.Abstract
Introduction: Pleural effusion is a prevalent medical disorder for which there are numerous potential causes. The causes of neutrophililic predominate exudative effusions are acute processes, such as acute pulmonary embolism or pneumonia, but the differential diagnosis for lymphocytic effusions is far lengthier. Nonetheless, malignancy and pleural tuberculosis are the most common causes of a lymphocytic pleural effusion in regions with a high TB incidence. Objectives of the study: to determine the lymphocyte counts and ADA levels in patients with suspected bilateral tubercular pleural effusion. Methodology: We included a total of 120 patients with and without bilateral tubercular pleural effusion. Patients with TPE are grouped as cases [TPE group], and patients without tubercular effusion as controls [Non TPE]. We had a total of 72 patients in Non TPE and 48 in TPE group. Pleural fluid was collected in all the patients for biochemical analysis and cell counts. The biochemical investigations included total protein, albumin, glucose and ADA estimation. Results and Conclusion: In the present study, we found statistically significantly elevated levels of
ADA in TPE compared to Non TPE. Lymphocyte counts were elevated in both the groups but in the TPE group the association between ADA levels and lymphocytes counts was not statistically significant.
