Clinical Profile of Kidney Injury in Hypertensive Patients: A Cross-Sectional Study

Abstract

Background: Hypertension is a leading risk factor for kidney injury, and it is estimated 
that up to 30% of hypertensive patients will develop kidney dysfunction. However, the 
clinical profile of kidney injury in these patients remains underexplored. 
Methods: This cross-sectional study was conducted at a tertiary care hospital over one 
year. A total of 250 hypertensive patients aged ≥18 years with serum creatinine ≥1.5 
mg/dL or an estimated glomerular filtration rate (eGFR) <60 mL/min/1.73m² were 
included. Exclusion criteria included patients with pre-existing kidney disease, 
diabetes, or other comorbidities. Data were collected through interviews, physical 
examination, and laboratory tests, including serum creatinine and eGFR. Causes of 
kidney injury were identified through clinical history, imaging, and biopsy. Logistic 
regression was used to identify risk factors associated with kidney injury.