Clozapine-Induced Perimyocarditis

Abstract

Atypical antipsychotic drugs are widely used in the treatment of schizophrenia due to their higher efficacy and better side-effect profile compared with traditional antipsychotic drugs. However, serious cardiac toxicity of these drugs can occur, and if not recognized early, can be fatal. In this report, we present a case of acute perimyocarditis following the initiation of Clozapine, a frequently used atypical antipsychotic drug, for the treatment of refractory schizophrenia, which completely resolved after the discontinuation of this drug.