A STUDY OF PRE-OPERATIVE AND INTRAOPERATIVE EVALUATION OF AUTONOMIC FUNCTIONS IN DIABETIC PATIENTS UNDERGOING NEUROSURGERY UNDER GENERAL ANAESTHESIA

Abstract

The Autonomic nervous system (ANS) controls involuntary activities of the body outside the normal realm of consciousness. Cardiovascular autonomic neuropathy is frequently observed in patients with diabetes mellitus. As anaesthesia has a marked effect on peri-operative autonomic function, the interplay between diabetic neuropathy and anaesthesia may result in unexpected
haemodynamic instability during surgery. The objective of this literature review was to examine the association of cardiovascular autonomic neuropathy with peri-operative cardiovascular complications. Depending on the type of anaesthesia, the presence of cardiovascular autonomic neuropathy in surgical patients can markedly affect peri-operative haemodynamics and postoperative recovery. Pre-operative testing of the extent of autonomic dysfunction in particular populations, like diabetics, may contribute to a reduction in haemodynamic instability and cardiovascular complications.