Trends and Seroprevalence of Transfusion-Transmissible Infections Among Blood Donors in Bihar: A Retrospective Institutional Analysis
DOI:
https://doi.org/10.48047/Keywords:
Seroprevalence, Transfusion-transmissible infections (TTI), Blood donors, Bihar, Voluntary donationAbstract
Background: The safety of blood transfusion is a critical concern in medical practice, as it provides
essential life support and improves health outcomes for patients in need.
Materials and Methods: This retrospective study included 2600 blood donors from January 2021 to
September 2024 at a tertiary hospital blood bank. Data on donor demographics and TTI screening results
for HIV, HBV, HCV, syphilis, and malaria were collected. Screening protocols utilized ELISA, CLIA,
RPR tests, and rapid diagnostics. Annual seroprevalence rates were calculated, and trend analyses with chisquare tests were conducted to examine statistical significance across years. Additionally, associations
between TTI positivity, donor type, and demographics were analyzed using SPSS version 25.0.
