A study of thyroid abnormalities in chronic kidney disease patients at tertiary care hospital

Abstract

Background: Chronic kidney disease is a progressive condition that affects >10% of the general population worldwide,
amounting to >800 million individuals. Thyroid hormones are required for the kidney's embryological development and 
growth. On the other hand, thyroid hormone metabolism, degradation, and elimination are all influenced by the kidney. 
Due to association between thyroid hormones and kidney function there will be a spectrum of abnormalities with respect 
to thyroid hormones in chronic kidney disease patients.
Objectives: To quantify thyroid function anomalies in people with chronic kidney disease and correlate them with 
severity of renal failure.
Settings & Design: A community based Cross sectional Study conducted in Kurnool.
Methods & Materials: A total of 200 non-dialysis chronic kidney disease patients attending nephrology department in 
government general hospital, Kurnool were considered as study population. T3, T4, TSH, Free T3& Free T4 were 
measured. Patients with past history of any medication for thyroid disorder or family history of thyroid disorder or history 
of any surgery or radiological exposure to thyroid gland were excluded from the study