Comparative Evaluation of Clinical Potential ofHuman Platelet Derived Growth Factor Gel Dressing and Conventional Dressing used in Oral Surgical Procedures: An Original Research Study

Abstract

Aim:The sole aim of this study was to compare and evaluate clinical potential ofhuman platelet derived growth
factor gel dressing and conventional dressing used in oral surgical procedures.Materials and Methods: This study
included total 30 patients including 21 male and 9 female patients. All patients have been explained about the study
in detail and informed consent obtained accordingly. All thirty patients have been studied equally into two study
groups (of fifteen each) as per their dressing material. In Group one patients, human platelet derived growth factor
gel dressing was used for wounds healing. In Group two patients, conventional dressing (povidone iodine) used was
used for wounds healing (control group). Patients were recalled in the post healing phase once a week up to three
weeks. To quantify the healing response, scoring system was utilized which has zero to ten scores. Results thus
obtained was compiled and sent for necessary statistical analysis. P value less than 0.05 was considered significant
(p< 0.05).Results:Statistical evaluation was completed by statistical software Statistical Package for the Social
Sciences version 21. Total 13 patients (maximum) were in age range of 24-29years. P value was found to be
significant in this age group (0.02). Two sample t- testassessments were attempted. This indicated superior clinical
performance of group one dressing material (human platelet derived growth factor gel). Fundamental statistical
description with level of significance assessment using pearson chi-square test for group I showed highly significant
P value. Comparison among the 2 study groups using one-way ANOVA showedhighly significant p value.
Conclusion:Authors concluded that clinical potential and healing performance ofhuman platelet derived growth
factor gel dressing was superior toconventional povidone iodine dressing.