Comparative Effects of Oral Pregabalin and Gabapentin on Postoperative Pain and Analgesic Consumption After Abdominal Hysterectomy- A Randomised Trial
DOI:
https://doi.org/10.48047/Keywords:
postoperative pain, pregabalin and gabapentin, abdominal hysterectomy, preoperative dose.Abstract
Objectives: This study was designed to evaluate and compare the efficacy of a single
preoperative doseb of pregabalin and gabapentin for attenuating postoperative pain and
analgesic consumption after abdominal hysterectomy.
Methods: 60 patients of ASA grade I or II were randomly allocated to three groups, with 30
patients in each group. Patients in Group P were given Pregabalin 300mg, Group G were
given Gabapentin 900mg 1 hour prior to surgery. Postoperative pain was assessed by a
100mm visual analogue scale.
Results: Postoperative pain and postoperative analgesic consumption was reduced in the
pregabalin and gabapentin group compared (P<0.05).
Conclusion: A single preoperative oral dose of Pregabalin 300 mg and Gabapentin 900mg is
an effective method for reducing postoperative pain and analgesic consumption in patients
undergoing elective abdominal hysterectomy. Pregabalin is a better pre-emptive analgesic as
compared to Gabapentin for decreasing post-operative analgesic consumption.
