LABORATORY PARAMETERS INTERPRETATION WITH CARDIAC MANIFESTATIONS IN COVID-19 PATIENTS

Abstract

Background: Coronavirus disease 2019 (COVID-19) has emerged as a major cause of morbidity and mortality. Both
COVID-19 and other pneumonias may present with elevated levels of T/I troponins suggesting injured myocardium.
Aim and objectives:to improve our understanding of the cardiac manifestations of COVID-19 without pre-existing
cardiovascular disease, and to provide insights into the characteristics of patients more susceptible to cardiovascular disease.
Subjects and Methods:At isolation hospital in Zagazig, and the isolation hospital in Tripoli, Libya, 42 COVID-19 positive
subjects were studied for their echocardiographic parameters, the study was carried out from March 5th 2021 to September
4th 2021.
Results: There was statistically significant difference in age but there was no statistically significant difference in sex in
relation to severity of disease where 69.2% of male were severe status vs 56.3% of female patients, patients with mild
disease were statistically younger than patient with severe disease where age of the studied patients in mild cases ranging
from 27-57 years old with mean 45.2 ± 11.9 years old while age of the studied patients in severe COVID-19 disease ranging
from 34-65 years old with mean 56.37 ± 7.4 years old. There was statistically significant difference in D.dimer , o2 saturation
and CT findings in relation to COVID-19 severity where d.dimer was statistically higher in severe disease patients than
moderate > mild cases (figure8), and O2 saturation was statistically lower in severe disease patients than moderate > mild
cases, there was no statistically significant difference regrading other laboratory investigation.
Conclusion: Our findings support findings of abnormalities in laboratory findings of COVID-19 patients correlated with
disease severity as well asD.dimer was statistically higher in patients with pulmonary hypertension , the cardiac monitoring
can provide us with important information which can help in management of covid-19 patients but we must consider risk of
contamination and transmission of disease