FORMULATION AND EVALUATION OF ROSUVASTATIN (ORAL DISINTEGRATING) TABLETS BY USING NATURAL POLYMER

Authors

  • Kameswara rao Sankula, Lakkimsetti Uma Mahitha, Menda Siva Parvathi, Sandaka Yasaswini, Desaboina Chandana, Mohammed Salma Begum. Author

DOI:

https://doi.org/10.48047/

Keywords:

Rosuvastatin (Drug), Banana powder, Croscarmellose sodium , Direct compression method.

Abstract

The present invention relates to the formulation of mouth disintegrating tablets of Rosuvastatin. Mouth
disintegrating tablets of rosuvastatin were successfully prepared using Banana powder and Croscarmellose sodium.
In the present study, mouth disintegrating tablets were prepared by direct compression method. The formulated
tablets were evaluated for parameters like hardness, friability, weight variation and drug content indicate that values
were within permissible limit for all formulation. The mouth disintegrating tablets of Rosuvastatin developed in this
investigation releases drug within 30 minutes. Thus, we are able to achieve our objective of preparing mouth
disintegrating tablets of Rosuvastatin with minimum excipients and simple method of manufacture

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Published

2021-05-29