IN-VITRO EVALUATION OF ANTI-DIABETIC ACTIVITY OF ETHANOLIC EXTRACT TRICHOLEPIS GLABERRIMA

Authors

  • CH K V L S N Anjana Male*, B. Devi, K. Chandrakaladar , P. Joy Nissi, K. Lilly Prasanna, V. Jyothi Author

DOI:

https://doi.org/10.48047/

Keywords:

Trichloepis glaberrima, Albino rats, Anti-diabetic activity, In vitro, Alpha amylase inhibition assay, Alpha glucosidase inhibition assay.

Abstract

Tricholepis glaberrima commonly known as “Brahmadandi” belongs to the family Asteraceae. It is prominently used by
traditional healers as an aphrodisiac. The plant contains several phytochemical constituents such as carbohydrates, flavonoids,
tannins, steroids and triterpenoids and glycosides. Even though so many allopathy are available but can act certain extent
only, hence there is a need for the traditional formulation development. With this aim we have started the research. In this
research we aimed to evaluate the anti-diabetic activity of ethanolic extract Trichloepis glaberrima using In-Vitro process.
The dried root of Tricholepis glaberrima was extracted with ethanol & was prepared by soxhlation using soxhlet apparatus
with ethanol as a solvent extract evaluated for anti- diabetic activity by In-vitro (i.e., by α -amylase inhibition assay, αglucosidase inhibition assay). From the results ethanolic extract Tricholepis glaberrima has exhibited significant anti-diabetic
activity.

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Published

2021-05-29