A REVIEW ARTICLE ON EBOLA VIRUS DISEASE

Authors

  • A.Uma Maheswari, Md. Ayesha Sultana, D. Mani Chandana, T. Nirmala Devi, R. Tejaswini Author

DOI:

https://doi.org/10.48047/

Keywords:

Zoonotic disease, Zaire species, Immunohistochemistry, Virus Isolation

Abstract

Ebola virus disease is a fatal zoonotic disease and it is very rare and dangerous one . It was identified in the year
1976 (almost 40 years back ) in the Democratic republic of Congo the reservoir host of EVD is still not clear.
These virus has 5 Different types or Species Zaire virus ,Sudan virus ,TIA forest virus , Bundibugyo virus, Reston
virus among them Zaire Species is the most dangerous one and which has high mortality rate it is transmitted from
non human primates to human and from humans to humans through body fluids ,blood exchanges or close contact
with Qarantined persons. According to studies many outbreaks were reported among them the longest outbreaks
occurred in the years 2001 – 2003 with fatality rate more than 80%. After that the biggest outbreak was recorded
in 2014- 2016 epidemic was West Africa with almost 30,000 cases and over 11,000 fatalities. The signs and
symptoms of EVD are fever ,hypovolemia and mainly Gastrointestinal symptoms like diarrhoea, vomiting and
other symptoms delirium, seizures .it can be detected by diagnostic methods like RT- PCR, ELISA testing, virus
isolation test Immunohistochemistry and other test. The Ebola virus has no cure but symptoms can be controlled.
It can be prevented by vaccination and by maintaining or practicing hygienic life style .The supportive care should
be provided to infected people

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Published

2021-05-29