Interpretation of Role of Both Perfluorooctane Sulfonateand Quercetin on Adult Liver

Abstract

Perfluorooctane sulfonate (PFOS) is one of the most widely used PFAS. This substance contains a hydrophobic and
lipophobic perfluoroalkyl chain and a sulfonic acid group that adds the polarity of this substance. These structural
characteristics support their applications and usage as water and oil repellents, firefighting foams, lubricants,
surfactant additives, and coating agents. Hepatotoxicity is chemical-driven liver injury.Exposure to PFOS can cause
oxidative damage to hepatocytes. Quercetin (QE)has been reported to be beneficial to human healthsuch as
osteoporosis, pulmonary and cardiovascular diseases, and aging.