Assessment of relation between diabetes mellitus and thyroid dysfunction

Abstract

Background:Thyroid diseases and diabetes mellitus are the two most common endocrine disorders encountered
in clinical practice. The present study was conducted to assess relation between diabetes mellitus and thyroid
dysfunction.
Materials & Methods:70 patients type II diabetes mellitus patients of either gender were assessed for fasting
blood glucose, glycosylated hemoglobin (HbA1C), lipid profile and urine albumin were performed. Estimation
of serum thyroid stimulating hormone, free triiodothyronine and free thyroxine were performed using
chemiluminescent immunoassay method.
Results: Males were 42 and females were 28. The mean age of patients was 48.7 years, mean BMI was 27.5
Kg/m2
, mean HbA1C level was 8.7% and duration of diabetes was 6.4 years. Serum T3 was normal in 80%,
increased in 12% and decreased in 8%. Free T3 was normal in 81%, increased in 4% and decreased in 15% and
free T4 was normal in 87%, increased in 9% and decreased in 4%. The maximum hypothyroidism patients (12)
were seen with >9 HbA1C level. Hyperthyroidism was seen in 10 with >9 HbA1C level.
Conclusion: Hypothyroidism was highly prevalent in diabetes patients as compared to hyperthyroidism.