Role of intracoronary adenosine on prevention of no reflow during Primary PCI in STEMI patients guided by MVO in CMR
DOI:
https://doi.org/10.48047/Keywords:
STEMI, Coronary no-reflow, MVO , MV HGE , Salvage Index, TIMI , MBG adenosine.Abstract
Background:Microvascular obstruction (MO) or no-reflow phenomenon is an established complication of coronary
reperfusion therapy for acute myocardial infarction. It is increasingly recognized as a poor prognostic indicator and
marker of subsequent adverse LV remodeling. Microvascular obstruction (MO) or no-reflow phenomenon is an
established complication of coronary reperfusion therapy for acute myocardial infarction. It is increasingly
recognized as a poor prognostic indicator and marker of subsequent adverse LV remodeling.
Results:There was no significant difference between two groups regarding TIMI and MBG score .There was a
significant difference in myocardial salvage index and myocardium at risk with p value less than 0.001 . Yet no
increase in myocardial hemorrhage among the two groups . There was significant improvement in EF , LV mass
and LV volumes in those who were given adenosine .
Conclusion:Adenosine improves no reflow on giving as a prophylactic drug . It improves the microcirculation thus
increasing the salvaged myocardium improving micro vascular obstruction and does not increase the percentage of
microvascular hemorrhage.
