ASSOCIATION OF MATERNAL TRIGLYCERIDES LEVEL WITH NEONATAL MACROSOMIA IN NON-OBESE NON-DIABETIC PREGNANT WOMEN

Abstract

INTRODUCTION: Maternal dyslipidemia experts potential and adverse impacts on
pregnant women and newborns. However, the association between maternal serum
triglycerides level and the risk of macrosomia has not yet been clearly studied.We did
this study for association between the maternal serum triglycerides level and risk of
macrosomia among the non-diabetic and non obese pregnant women.
OBJECTIVE: To find the associations of maternal triglyceride levels with neonatal
macrosomia in non-obese and pregnant women without Diabetes Mellitus . SETTING:
SCB Medical College, Cuttack, Odisha, India. MATERIAL AND METHOD: This
was a escriptive cross-sectional study of 100 pregnant patients with BMI less than
30. The medical records of 100 non obese and non-diabetic pregnant women at term
were prospectively analyzed. Maternal fasting serum triglyceride levels were
measured during late pregnancy. Scatter diagram was used to analyze the variables
associated with the risk of macrosomia.RESULTS:Maternal TG level was higher in
patient with macrosomia babies (333.00 ± 51.62) compare to those without
macrosomia (253.15 ± 81.02). This difference in mean was statistically significant (P
value = 0.001) (Table 5). There was a positive correlation between birth weight and
maternal triglyceride level which was statistically significant with correlation
coefficient value of 0.278 (r) and p value of 0.005. CONCLUSION:Our findings
highlight the importance of maternal lipid metabolism in fetal overgrowth and may
have implications for the etiology and primary prevention of macrosomia. However,
further prospective investigations involving larger population and basic research
studies are necessary to fully evaluate their clinical value and the mechanisms