DENTINOGENIC GHOST CELL TUMOR - A CASE REPORT

Abstract

Gorlin et. al first described the term “calcifying odontogenic cyst” (COC).[1] Not all of these
lesions are cystic and the biological behaviour is often not compatible with a cyst.[2] This
dualistic concept evokes a controversy whether COC is a cyst or tumor. Few authors consider
COC to have 2 entities: a cyst and a neoplasm. The WHO classified all COCs to be
neoplasm. The cystic lesionsare termed as “calcifying cystic odontogenic tumors” (CCOT)
and the neoplastic entity as a “Dentinogenic ghost cell tumor”(DGCT).[3]
DGCT is a rare tumor accounting for only 11.5% of all COCs.[2] Age of incidence is usually
in the elderly with a male predilection. It commonly involves the anterior segment of the
jaws. [2] Microscopic features comprise of ameloblastomatous epithelial islands, with areas
of ghost cell formation and varying amount of dentinoid material.