To evaluate the role of PCT as a prognostic marker in sepsis and its importance in outcome and mortality

Abstract

Background & Method: The aim of this study is to evaluate the role of PCT as a prognostic
marker in sepsis and its importance in outcome and mortality. After taking all aseptic precautions
blood samples were drawn from all patients within 24 hours of admission to the ICU for
hemoglobin, total leukocyte count, erythrocyte sedimentation rate, serum total bilirubin, SGPT,
blood urea, serum creatinine, blood culture and estimation of serum Procalcitonin. Day zero was
defined as the first observational day at admission, and the next day was named day 1, then day
2, and so on.
Result: Out of 100 patients, 20 patients were deceased and 80 patients were survived in our
study. A significantly higher proportion of non survivors demonstrated higher PCT
concentrations as compared to those who were alive at ICU discharge. By using Chi-square test
the difference was found to be statistically significant (P = 0.015).
Conclusion: The current review was an endeavor to evaluate the convenience of Procalcitonin as
a biomarker of sepsis in the early delineation of grown-up patients confessed to the emergency
unit thought sepsis. The review results uncovered that the expansion of serum procalcitonin to
the standard work-up of basically sick patients with thought sepsis could increment
demonstrative sureness and help in better persistent administration. Nonetheless, further huge
scope studies are prescribed to assess the symptomatic as well as prognostic utility of PCT in
ICU setting of tertiary consideration medical clinics in India.