Modified Left Ventricular Fetal Myocardial Performance Index: A CaseControlled Study

Abstract

Background:Modified left ventricular fetal myocardial performance index (MPI) is a pulse
wave Doppler index that can be utilized to assess global fetal myocardial function . Fetal MPI
is handily performed non- invasive method for the assessment of foetal cardiovascular wellbeing. Aim: This study aimed to access normal values for foetal modified left ventricular
(LV) MPI and its correlation with heart rate and gestational age among foetuses in central
India.Material and Methods:In our study, total seventy-one singleton pregnant women with
normal pregnancy were included. The Mod-LV MPI was calculated as the ratio of sum of the
isovolumetric constriction time (ICT) and isovolumetric relaxation time (IRT) upon ejection
time (ET). MPI = ICT+IRT/ ET. We also assessed correlation of MPI with foetal heart rate
and gestational age.Results:The normal mean MPI of second and third trimester foetuses of
Indian population was 0.409±0.052. Mean ICT was 45.7 ± 7.0ms, mean IRT was 55.9 ±
6.7ms, and mean ET was 148.2 ± 10ms. The mean FHR was 142.26 ± 5.8 bpm and mean
gestation age (weeks) is 33.16 ± 4.8. The coefficient correlation analysis reveals MPI is
independent of both gestational age and FHR.Conclusion:Our study gives the normal range
of MPI in the normal heart foetuses of the Indian population and it also shows that MPI is
independent of gestational age and FHR. Thus, MPI ought to be utilized for the underlying
initial assessment of the foetal heart and babies with congenital heart defect just as for the
follow up of foetuses with a heart defect. MPI is additionally conceivably helpful for
evaluation the foetal cardiac status in noncardiac disease state.