Reported Analytical Methods of Metformin: An Extensive Review

Abstract

Metformin, a widely prescribed oral antidiabetic drug, plays a crucial role in managing type 2 diabetes 
by improving glycemic control. Given its extensive use, the accurate and reliable determination of 
metformin in pharmaceutical formulations, biological fluids, and environmental samples is essential 
for quality control, therapeutic monitoring, and environmental safety. This review provides a 
comprehensive overview of the various analytical methods reported for the quantification of 
metformin.