“TO STUDY THE MOLECULAR CHARACTERIZATION OF X-RAY CROSSCOMPLEMENTING GROUP 1 (XRCC1) GENE AND ITS ASSOCIATED RISK FACTORS IN SENILE CATARACT PATIENTS”

Abstract

Introduction: Cataracts are caused by the ageing of the crystalline lens of the eye, which prevents clear vision. 
X-ray cross-complementing group 1 (XRCC1), a DNA repair protein involved in single-strand breaks (SSBs) 
and BER pathway, has been reported to be responsible for the efficient repair of DNA damage caused by active 
oxygen, ionization, and alkylating agents is mainly responsible for cataract in patients.