Study of Infertility in Polycystic Ovary Syndrome

Abstract

Background: Polycystic ovarian syndrome (PCOS) is a frequently occurring metabolic
and reproductive endocrinopathy. Young women with PCOS mainly present with
reproductive problems such as hyperandrogenism (HA), menstrual irregularities, infertility
and chronic anovulation. Infertility increases 10 folds in women with PCOS and affects up
to 40%. PCOS reduces fertility due to associated endocrine, metabolic and gynecological
abnormalities that impact on the quality and function of the ovary. Clinically, PCOS is
characterized by either oligoovulation or anovulation and HA that may cause infertility,
and other related metabolic disorders. The infertile patients with PCOS had statistically
higher occurrence of an ovulatory cycle with oligomenorrhoea, hirsutism and serum
testosterone levels compared to infertile women with normal ovaries.