Expression Of Lipocalin-2 (LNC2) Gene In Polycystic Ovarian Syndrome (PCOS) Patients As Diagnostic Biomarkers

Authors

  • Hanan Waleed Muhamed AL-SAMMARRAIE , Raghad Hazem Alabbasy , Ibrahim Samer Al-Badri Author

DOI:

https://doi.org/10.48047/

Keywords:

lipocalin-2, PCOS, ELISA technology, qRT-PCR, insulin resistance markers

Abstract

Background: Recently, research has been conducted on proteins such as lipocalin-2 (LNC2) and 
peptides that play roles in regulating metabolism, and also research has been conducted on the 
level of lipids and lipoproteins such as [cholesterol and triglycerides, LDL ,VLDL] which can be 
considered as potential markers of insulin resistance in some patients. Medical conditions, such 
as diabetes, obesity, and polycystic ovary syndrome (PCOS). gained in interest. Polycystic ovary 
syndrome (PCOS) is a common endocrine disorder associated with hyperandrogenemia and 
anovulatory failure, which is often accompanied by metabolic disorders, including obesity, 
dyslipidemia, hyperinsulinemia, and insulin resistance. Methods: Venous blood samples (5 ml) 
were collected from 200 women representing two groups.

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Published

2024-11-01