An Overview On Anti-Ages Therapy: Mini Review

Abstract

Non-enzymatic glycosylation is glycation between protein and reducing sugar transforming into the
formation of advanced glycation end products (AGEs). Many of the epidemiological studies have
demonstrated a strong correlation between the formation of AGEs with the pathogenesis of several chronic
complications like inflammation, diabetes, nephropathy, retinopathy, neuropathy, atherosclerosis, and
cancer. Besides, considering AGEs as lethal components, there are still very fragmentary research on the
discovery and development of AGEs inhibitors. One of the causes may be the lack of awareness about the
importance of anti-AGEs in the said disorders. The discovery and investigation of compounds with an
AGEs inhibitor activity may offer a potential therapeutic approach for the prevention of such several
pathogenic complications. The present review summarizes research on anti-AGEs products in chronic
complications like inflammation, atherosclerosis, diabetes, cancer and several other disorders.