Biochemical Variations of Serum Magnesium with Lipid Analytes in Different Clinical Groups of Type 1 and Type 2 Diabetes Mellitus- An Original Research

Abstract

Background: The present study was undertaken for assessing biochemical Variations of Serum Magnesium
with Lipid Analytes in Different Clinical Groups of Type 1 and Type 2 Diabetes Mellitus.
Materials & methods:100 subjects were enrolled in the present study. All these 100 subjects were cases of
diabetes mellitus. Another set of 100 normoglycemic healthy subjects were taken as controls. Complete
demographic and clinical details of all the subjects were enrolled. All the subjects of the study group were
divided into two groups: T1DM (Type 1 diabetes mellitus) and T2DM (Type 2 diabetes mellitus). All the
patients of the study group were further subcategorized into three sub-groups: Subgroup I, Subgroup II and
Subgroup III. Subgroup II: Newly diagnosed cases of DM not under any treatment. Subgroup II: Stabilized DM
under treatment. Subgroup III: Long course, uncontrolled DM associated with noted complications. Blood
samples were obtained from all the patients and magnesium levels along with serum lipid analytes
triacylglycerol (TAG) and total cholesterol were measured. All the results were recorded and analyzed by SPSS
software.
Results:Significant results was obtained while comparing fasting plasma glucose levels, serum magnesium
levels, serum total cholesterol level and serum triglycerides levels between healthy controls and subgroup I and
in between healthy controls and subgroup III. Non-significant results were obtained while comparing the mean
plasma glucose levels, serum magnesium levels, serum total cholesterol level and serum triglycerides levels
among T1DM patients and T2DM patients among various subgroups.
Conclusion:Physicians should prescribe serum magnesium as a routine investigation of diabetes diagnostic
profile for preventing long-standing critical diabetes complications.