Correlation betweenQuantitative C-Reactive Protein and Dialysis Duration: A Study of Twice-a-Week Hemodialysis Patients

Abstract

Introduction. The correlation between quantitative C-reactive protein (CRP) and dialysis duration in twice-aweek hemodialysis patients has not been examined extensively. This study aimed to examine the relationship
between quantitative CRP and dialysis duration in twice-a-week hemodialysis patients.
Methods. It involved cross-sectional observation of 62 hemodialysis patients at H. Adam Malik General
Hospital, Medan, Indonesia, between March and October 2019. Interviews, clinical examinations, and a review
of medical records were used for data collection. Hematology analyzer was used to measure the Blood Urea
Nitrogen (BUN), Hemoglobin, creatinine, and differential leucocyte counts, while colored latex
immunofiltration assays (IFAs) was used to analyze the qualitative CRP. The correlation between quantitative
CRP and dialysis duration and hemoglobin assessed using the Spearman’s correlation test.
Results. The result did not show any correlation between quantitative CRP and dialysis duration (r = 0.091; p =
0.240), but there was a significant inverse correlation between dialysis duration and hemoglobin (r = -0.234; p =
0.033) and a significant inverse correlation between quantitative CRP and hemoglobin (r = -0.144; p = 0.032).
Conclusion. This study revealed that there was no significant correlation between quantitative CRP and dialysis
duration, but it was correlated with low hemoglobin twice-a-week in hemodialysis patients. The findings of the
report provide the basis for further study.