A Comparison of Two Different Doses of Intravenous Dexmedetomidine to Attenuate Hemodynamic Responses to Direct Laryngoscopy and Intubation in Adult Patients Undergoing Elective Surgeries under General Anaesthesia: A Prospective Observational Study in

Abstract

Background
Laryngoscopic manipulation and the process of endotracheal intubation can trigger harmful 
responses, such as increased heart rate, irregular heart rhythms, and elevated blood pressure.
The aim of the study is to compare the efficacy of two different doses of dexmedetomidine 
(0.5mcg/kg and 0.75mcg/kg) for attenuation of hemodynamic response to laryngoscopy and 
endotracheal intubation in adult patients undergoing elective surgeries under general 
anaesthesia and to determine dose dependent side effects like hypotension, bradycardia and 
sedation.