A Study of Effects of Antiepileptic Drugs on Lipid Profile in Subjects with Seizure Disorder

Abstract

Background
In India, 12 million people suffer from epilepsy and bears 1/6 of the world's weight.1 Epilepsy has 
an incidence of approximately 0.3-0.5% in various groups worldwide with a prevalence estimated 
at 5–30 persons per 1000.2
It has been observed that antiepileptic drugs (AED) raise serum levels 
of lipoproteins, total cholesterol and low-density lipoprotein (LDL) which accelerate 
atherosclerosis and risk of vascular illness.3 As there is chronic use of AED for epilepsy, 
chronic neuropathic pain, migraine, there is need for study to determine AED effect on Lipid 
profile.