Role Of Inflammatory Markers In Acute Exacerbation Of Chronic Obstructive Pulmonary Disease

Abstract

Background It is estimated that there are around 3 million deaths annually due to COPD worldwide. According to WHO 
COPD is 3rd leading causes of death worldwide.
COPD is characterized by progressive destruction of the pulmonary parenchyma frequently. The result of response to 
external stimuli (i.e long term exposure of cigarette smoking, environmental pollution) which culminates the progressive 
airway limitation. Inflammation in COPD may play a role via various cell type like neutrophil ,macrophages and 
lymphocyte. In this regard scientist have devoted their attention to the ratio of some of inflammatory markers as for 
examples, neutrophil to lymphocyte Ratio and platelet to lymphocyte ratio to know the role in systemic inflammation.