Pattern of Isoniazid Monoresistance among Pulmonary Tuberculosis Patients at Tertiary Care Centre

Authors

  • Dr Vibhuti Zankat , Dr Rashmika Parmar , Dr Hitesh Shingala , Dr Payal Mankodi Author

DOI:

https://doi.org/10.48047/

Keywords:

Pulmonary tuberculosis, Isoniazid, Kat G gene mutation, InhA gene mutation

Abstract

Introduction: Tuberculosis is an infectious disease, which remains killer disease of all 
times. Drug resistance in the first line drugs makes the situation worse. Major obstacle in the 
management of tuberculosis is emergence of drug resistance. The molecular line-probe assay 
provides rapid diagnosis and early management of MDR-TB. It detects mutations of katG and 
inhA genes associated with isoniazid (INH) resistance in Mycobacterium tuberculosis 
isolates. 

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Published

2024-11-01

Issue

Vol. 15 No. 11 (2024): volume 15 issue 11 (2024)

Section

Articles