Pattern and presentation of ANA by Immunofluorescence and Line Immuno Assay

Abstract

Background: Autoantibodies are the hallmark of autoimmunity, of which anti-nuclear antibody 
(ANA) is of key importance. ANA has the capability of binding and destroying certain structures 
within the nucleus of the cells. ANA are detected in the serum of patients suffering from 
autoimmune diseases. There is therefore a need to evaluate the pattern of ANA positivity in 
autoimmune diseases in Indian settings.