Low dose dopamine in prevention of GFR deterioration in acute decompensated heart failure with preserved ejection fraction.

Abstract

Background: Low dose dopamine use in acute decompensated heart failure (ADHF) still lacks evidence. Our objective was to establish the value of low dose dopamine in ADHF patients withpreserved ejection fraction in prevention of glomerular filtration rate (GFR) deterioration, duration of hospital stay, 6 months cardiovascular (CV) mortality & rehospitalization. Methods: One hundred ADHF patients with preserved ejection fraction admitted to Benha&Alzaytoon cardiology departments were randomized into 2 groups, each composed of 50patients: group A received conventional ADHF treatment + low dose dopamine &group Breceived only conventional ADHF treatment. Patients of both groups were observed for duration of hospital stay, GFR changes, 6 months cardiovascular (CV) mortality & re-hospitalization.