Association of Amylin Polypeptide and Inflammatory Biomarkers in Diabetic Coronary Artery Disease

Authors

  • Zunjarrao G. Badade, Yogita Mahendra Shinde, Shibban K. Kaul, Sandeep Rai, Sameer Sudhirchandra Kadam, Shilpa Amardeep Kadam Author

DOI:

https://doi.org/10.48047/

Keywords:

cardiac myocytes, hyperamylinemia, insulin resistance, inflammatory mechanism, proteotoxicity

Abstract

Introduction: Type 2 diabetes mellitus (T2DM) and coronary artery disease (CAD) poses major threat worldwide contributing to excessive morbidity and mortality, these co-morbidities synergistically interact with inflammatory mechanisms.  Amylin is fraternal twin of insulin, it has a great potential to fibrillation, aggregate formation, and deposition causes proteotoxicity to vital organs.

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Published

2021-02-13

Issue

Vol. 12 No. 1 (2021): volume 12 issue 1 (2021)

Section

Articles