FORMULATION OF ORAL DISPERSIBLE FILM OF FUROSEMIDE AND COMPARATIVE STUDY OF NATURAL AND SYNTHETIC SUPERDISINTEGRANT INCORPORATED

Abstract

This study aims to construct and characterise oral films of furosemide made by solvent casting method based on Lepidium sativum and synthetic disintegrant. The films were made with PEG-400 acting as a plasticizer, Lepidium sativum mucilage acting as a natural disintegrant, and copovidone acting as a synthetic disintegrant. HPMC was used as the film-forming polymer.