THE ROLE OF VIRAL INFECTIONS IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE: INSIGHTS FROM A PATHOLOGICAL CROSS-SECTIONAL STUDY

Abstract

Background: Chronic Obstructive Pulmonary Disease (COPD) is a progressive respiratory condition with multifactorial origins, including environmental, genetic, and infectious components. Recent research suggests that viral infections could play a significant role in exacerbating and potentially driving the progression of COPD. Methods: This pathological cross-sectional study investigated the prevalence and impact of viral infections in individuals diagnosed with COPD. Utilizing a sample of 200 patients with confirmed COPD, viral pathogens were identified through polymerase chain reaction (PCR) assays of sputum samples. Pathological assessments were conducted to evaluate the extent of lung damage and correlate these findings with the presence of viral infections. Results: Preliminary analysis indicates a higher prevalence of respiratory viruses in COPD patients compared to control subjects. Detailed pathological examination revealed significant correlations between viral presence and increased lung tissue damage.