Study of Thyroid Function in Rheumatoid Arthritis Cases Admitted in A Tertiary Care Center

Abstract

Background: Rheumatoid arthritis (RA) is a chronic and systemic autoimmune disease that
causes persistent inflammatory polyarthritis and joint degradation, limiting mobility and
increasing disability.1 The frequency of RA in the general population is about 1%, and it has
been linked to a number of co-morbidities.2 The aetiology of RA is still unknown, and both
genetic and environmental variables have a role in the disease's development.3 Despite the
clinical implications of RA, patients with the condition are more likely to develop comorbidities, such as cardiovascular disease (CVD) Aim & Objective: 1.Study of thyroid
function in rheumatoid arthritis cases.2. Study prevalence of thyroid disorder among RA
factor positive patients. Methods: A Cross sectional study. Study setting: Department of
Physiology Grant Government medical college, Mumbai. Study duration: 1 year (5/08/19 to
4/08/20)
Study population: A total of 100 RA patients were recruited from the Outpatient and Inpatient
department of Medicine at Grant Government medical college, Mumbai during study period
5/08/19 to 4/08/20 Sample size: 100 Results: Most of cases found in above 60 years age
group 70 cases followed by 38 cases in 46 to 60 years age group, 24 cases in 31 to 45 years
age group and 8 cases in 18 to 30 age group, most of cases were females 82 and 18 males,
majority cases presented with Subclinical hypothyroidism 12 cases followed by
Hyperthyroidism 8 cases and Hypothyroidism 3 cases, HTN 10 cases, DM 5 cases, 2 cases
presented with COPD. Conclusions: Most of cases found in above 60 years age group, most
of cases were females, majority cases presented with Subclinical hypothyroidism