CEREBROVASCULAR INVOLVEMENT IN PATIENTS WITH COVID19 ASSOCIATED MUCORMYCOSIS IN TERTIARY CARE CENTRE

Abstract

Background
This study scrutinizes the prevalence and demographic determinants of rhino-orbito-cerebral
mucormycosis (ROCM) in the context of various factors including age, gender, and diabetic
conditions, delineating clear patterns and potential risk factors that may contribute to the
onset and exacerbation of ROCM.
Methods
This cross-sectional study was conducted to investigate the cerebrovascular involvements in
patients diagnosed with COVID-19 associated mucormycosis (CAM) at hospitals affiliated
with BMCRI. The study spanned from May 2021 to August 2021, during which time
pertinent data from 49 patients were meticulously recorded and analyzed.
Results
The results underscored a significant gender disparity in ROCM prevalence, with males being
more predominantly affected (p <0.05)[13]. Furthermore, the age group of 50-60 showed a
heightened vulnerability to ROCM, especially amongst individuals with pre-existing diabetic
conditions (p <0.001)[15,17,19]. Noteworthy was the exacerbation of symptoms and
complications in patients with a history of steroid usage (p <0.01)[20]. A considerable
portion of the cases also delineated a discernible difference in clinical outcomes between Mucor and Aspergillus infections in ROCM, paving the path for focused clinical
strategies[21].
Conclusion
The study furnishes critical insights into the demographic precursors of ROCM, spotlighting
age and diabetic conditions as potent risk factors. The findings beckon an immediate need to
tailor medical interventions and community health programs that address these specific
demographics, thereby potentially curtailing the incidence and severity of ROCM. Further
research is advocated to establish a more intricate understanding of the disease dynamics.