Reactive Thrombocytosis in Tuberculosis-

Abstract

Background: Tuberculosis is a major public health problem in India and it remains an
epidemic. hematological changes are commonly associated with TB, data regarding this are
lacking in the study area. As hematological changes associated with TB determine its
treatment and prognosis, identifying these is crucial for its prompt management. The present
study is carried out to know the importance of varied heamotological parameters like
thrombocytosis in tuberculosis and its relevance as a marker in diagnosing and treatment of
tuberculosis. Materials And Methods: It is a prospective case control study conducted in
GIMS in patents attending chest and TB ward and OPD during period of July 2022 to June
2023, a total of 12 months. Sample size is 54 pts. Investigations like CBC with platelet count,
ESR, LFT, RFT, sputum for AFB, sputum gram staining, CXR, CT chest, ultrasound of the
chest / abdomen and body fluid examination done. Results: There are 68(97.14%) patients in
control group with Platelet count less than 450 and only 2 (2.8%) with platelet count more
than 450X103 /ml. Whereas in TB patients group, there are 22 (40.74%) patients with platelet
count less than 450X103/ml and 32(59.25%) patients with platelet count of more than
450X103 /ml. Conclusion: As thrombocytosis is more seen in tuberculosis cases compared
to age and sex matched controls, Just like ESR,a simple test like thrombocytosis can be used
as heamotological marker for identifying a TB suspect which can be confirmed later by
various relevant tests.