To analyze the efficacy of iv labetalol 0.25/mg/kg in attenuation of haemodynamic response to extubation

Abstract

Background: The surgeries performed with securement of airway with endotracheal tube
placement will be followed by extubation at the end of surgical procedure. Extubation may be
associated with upper airway obstruction, laryngospasm, bronchospasm, tachycardia, hypertension and dysrhythmiasTracheal. Extubation evokes various haemodynamic stress response in the form of tachycardia, raised blood pressure,changes in the heart rhythm which is detrimental to susceptible patients. Hence a study is needed to find a pharmacological drug to attenuate the stress response to extubation.