Evaluation of Serum Folic Acid and Vitamin B12 levels in Patients of Vascular Dementia in North India

Abstract

Background: In the 21st century, dementia is the greatest global health and social care challenge. Vascular dementia is characterized as cognitive impairment caused by a cerebrovascular disease or cardiovascular dysfunction results in an ischemic, hypoperfusion, or haemorrhagic brain lesion. Objectives: To appraise serum folic acid and vitamin B12 levels and their correlation with the socio demographic variants and clinical variants in patients with vascular dementia. Methodology: In this case-control study, 40 patients with vascular dementia and 20 healthy controls were selected. Serum levels of folic acid and vitamin B12 were estimated by immunodiagnostic assay using luminescent reaction.