SERUM URIC ACID LEVELS AND CARDIOVASCULAR OUTCOMES IN ACUTE CORONARY SYNDROME- 30 DAY FOLLOW UP
DOI:
https://doi.org/10.48047/Keywords:
acute coronary syndrome, myocardial infarction, Uric acid, hyperuricemia, heart failure, death, mortality.Abstract
Coronary artery disease is a leading cause of morbidity and mortality globally. Various risk
factors for the development of cardiovascular disease are known, however, the role of uric acid has been debatable. Patients more than 40 years of age diagnosed as Acute Coronary
Syndrome were admitted and observed for in hospital course, in-hospital mortality and then
were followed up at 30 days after discharge. The patients were stratified according to uric acid
level as normouricemia and hyperuricemia and the observations were made. We found that
hyperuricemia was seen more in patients with diabetes, dyslipidemia, obesity and smokers. Inhospital course was more complicated in patients with hyperuricemia. Heart failure,
arrhythmias, cardiogenic shock and in-hospital mortality were significantly higher in
hyperuricemic patients. Hyperuricemia was also associated with more severe coronary artery
disease. 30 day MACE rate was significantly higher in patients with baseline hyperuricemia
driven mainly by cardiovascular death and reinfarction
