EFFICACY OF LIGNOCAINE VS DEXMEDETOMIDINE FOR ATTENUATION OF HEMODYNAMIC STRESS RESPONSE TO LARYNGOSCOPY AND INTUBATION

Abstract

Background: Direct laryngoscopy and endotracheal intubation following induction of anesthesia may trigger sympathetic and sympathoandrenal responses causing profound variation in cardiovascular physiology, and may cause serious complications in patients with underlying coronary artery disease, hypertension, or intracranial neuropathology. Present study was planned to evaluate the effect of IV dexmedetomidine infusion and IV lignocaine in attenuating the hemodynamic responses during laryngoscopy and intubation.